Setting the Record Straight?
Two years later, research published in Gastroenterology2 sought to put the German study’s claims to rest. Based on an analysis of 13,864 participants from the Nurses’ Health Study, the study authors reported that there was “no convincing evidence that PPI use increases dementia risk.” It’s important to remind readers that this study was sponsored by the American Gastroenterological Association, which may have had some bias. Still, the study’s authors did note that, for many patients, lifestyle modification including weight loss, avoiding tobacco, and adopting a healthier diet could reduce the need for PPIs in the first place. But others may suffer from more complex gastrointestinal issues that are tougher to treat. Either way, I suggest making healthy lifestyle tweaks first. For temporary relief, try this old home remedy: sodium bicarbonate (baking soda) mixed in a glass of water. It neutralizes acidity quite well, and can even be safely done for a few days. But from what I understand, it’s not safe as a long-term solution. If your heartburn or acid reflux persists, consult with a trusted healthcare professional.- JAMA Neurol. 2016;73(4):410-416
- American Gastroenterological Association. (2017, July 20). Setting the record straight: PPIs do not cause Dementia. ScienceDaily. Retrieved April 18, 2019 from www.sciencedaily.com/releases/2017/07/170720095314.htm